In Florida the Giant whitefly is known to attack a number of ornamental plants, but is most serious a pest on Hibiscus. In California it has been recorded from dozens of different plant families. Upon hatching from the egg the first instar nymph tends to remain within the circles of eggs on the leaf surface, and as it moves to the next stage it loses its legs and feeds without moving. The third and fourth instar nymphs create the majority of the long wax filaments, and these often become matted on the surface of the leaf to create a tangle of wax, honeydew, and the sooty mold that develops. A generation is completed in about 35 days, with numerous generations each year possible.
Attempts are being made to introduce a successful parasitic wasp into infested areas, but the results have not been highly effective. Chemical controls currently have little history with this species, but a systemic such as imidacloprid may be somewhat effective.